Xeomin vs. Botox: Which Wrinkle Treatment Is Right for You?
When it comes to smoothing fine lines and wrinkles, many patients ask the same question: Should I choose Xeomin or Botox? At Perizia Aesthetics in Jupiter, Florida, we specialize in advanced injectable treatments that produce natural-looking, individualized results. While both options are FDA-approved and effective, we typically recommend Xeomin for its purified, additive-free formulation and long-term reliability.
In this article, we’ll break down the science, benefits, and differences between Xeomin and Botox, drawing on clinical research, expert insight, and FDA data. By the end, you’ll better understand which wrinkle treatment aligns with your goals—and how our team can help you decide with confidence.
For questions or to schedule a consultation, call us at 561-318-7895 or book online today.
Understanding Wrinkle Treatments
Wrinkle treatments like Xeomin and Botox work by addressing one of the root causes of facial aging: repeated muscle contractions. Every time you frown, smile, or squint, your facial muscles contract and create creases in the skin. Over time, these creases become etched in place as wrinkles.
Both Xeomin and Botox contain botulinum toxin type A, which temporarily blocks nerve signals to targeted muscles. This allows the skin above to relax and smooth out. Treatments are non-surgical, minimally invasive, and results typically last for several months.
According to the FDA prescribing information for Xeomin, injections should not be repeated more frequently than every three months, helping patients maintain results safely over time.
What Is Xeomin?
Xeomin is an FDA-approved injectable designed to treat moderate-to-severe glabellar lines (the frown lines between your eyebrows). Unlike Botox, Xeomin is considered a “naked” or “pure” neurotoxin, meaning it does not contain accessory proteins—only the active botulinum toxin type A.
This purity has important implications. Research suggests that Xeomin’s simplified formulation may reduce the risk of patients developing antibody resistance, a rare condition where the body becomes less responsive to treatment over time (PMC).
The FDA-approved dosing for Xeomin is 20 units for frown lines, divided into five small injections of four units each. Clinical data shows that Xeomin begins working within 3 to 7 days, and its effects usually last about 3–4 months, with some patients reporting results for up to 6 months (Healthline).
Another practical advantage is that Xeomin does not always require refrigeration before use, simplifying handling for clinics (Facial Esthetics Institute).
At Perizia Aesthetics in Jupiter, FL, we offer Xeomin treatments as part of our tailored wrinkle care, helping patients achieve a natural, refreshed appearance.
What Is Botox?
Botox is perhaps the most recognized name in aesthetic medicine. FDA-approved for multiple uses—including glabellar lines, forehead lines, and crow’s feet—it has a long track record of safety and effectiveness.
Botox contains the same active ingredient as Xeomin, botulinum toxin type A, but with complexing proteins attached. While these proteins do not directly influence results, they are part of the formulation and contribute to Botox’s distinctive brand history (Drugs.com).
In terms of onset and duration, Botox is very similar to Xeomin. Patients typically see results within a few days, and the effects last 3–4 months depending on dosage, injection sites, and individual metabolism.
The long history of Botox use has provided extensive safety data, making it a trusted option for millions of patients worldwide (Healthline).
Xeomin vs. Botox: Side-by-Side Comparison
While both injectables share many similarities, there are important differences worth noting:
Feature | Xeomin | Botox |
Formulation | Pure neurotoxin, no accessory proteins — reduces unnecessary exposure | Toxin with complexing proteins |
FDA-Approved Areas | Glabellar lines | Glabellar lines, forehead lines, crow’s feet |
Onset of Results | 3–7 days | 3–7 days |
Duration | Lasts ~3–4 months, often up to 6 months | ~3–4 months |
Immune Response | Lower risk of antibody resistance due to purified formula | Slightly higher potential due to added proteins |
Storage | Stable at room temperature — does not require refrigeration | Typically requires refrigeration |
Safety Profile | Similar to Botox | Similar to Xeomin |
A split-face clinical trial published in Plastic & Reconstructive Surgery compared Xeomin and Botox directly. Patients received Botox on one side of the forehead and Xeomin on the other. The study found no difference in onset or duration, supporting the idea that both are equally effective when dosed correctly.
Further analysis from the National Library of Medicine reported no significant differences in safety or efficacy between the two, although some studies suggested a slight variation in dose ratios.
At Perizia Aesthetics, we offer Xeomin and recommend it as a trusted alternative to Botox. While both are widely recognized neuromodulators, we guide patients toward Xeomin for its purified formulation and effective results, ensuring the option best suited to their aesthetic goals is readily available in our clinic.
Who Is Xeomin Best For?
Xeomin is often recommended for patients who want a pure neurotoxin formulation without accessory proteins. This can be especially appealing for individuals concerned about the possibility of antibody resistance developing with repeated treatments (Drugs.com).
It is also a strong option for:
- Patients new to wrinkle treatments who want an effective and modern solution.
- Individuals seeking a treatment with potentially lower immunogenicity.
- Those who want results comparable to Botox but are interested in trying a newer alternative.
At Perizia Aesthetics in Jupiter, Xeomin is carefully administered by skilled injectors to deliver natural-looking results tailored to your facial structure.
Who Is Botox Best For?
Botox may be the best choice for patients who value a product with a longstanding safety record and FDA approval for multiple treatment areas.
It is often chosen by:
- Patients who want a trusted, globally recognized brand.
- Long-term users who have consistently seen reliable results.
Individuals who prefer a product with the largest body of long-term clinical data (Healthline).
Safety, Side Effects, and What to Expect
Both Xeomin and Botox have very similar safety profiles. Common side effects may include:
- Mild injection site pain or redness
- Temporary bruising
- Headache
- Drooping eyelid or eyebrow in rare cases
More serious side effects are rare but can include muscle weakness or difficulty swallowing if the toxin spreads beyond the treatment area. These risks are carefully managed by using FDA-recommended dosing and precise injection techniques (Xeomin Prescribing Guide).
At Perizia Aesthetics, all treatments are performed by trained professionals in a medical setting. We take time to review your health history, discuss expectations, and ensure that your wrinkle treatment experience is both safe and effective.
Cost and Value Considerations: Why Xeomin Makes Sense
When comparing Xeomin and Botox, many patients naturally ask about cost. Both treatments are priced per unit, but the total cost depends on several factors, including:
- Number of treatment areas
- Individual muscle strength and facial anatomy
- Units needed to achieve optimal results
While per-unit pricing may vary slightly between practices, the true value lies in expert dosing, precision application, and long-lasting results. At Perizia Aesthetics, we recommend Xeomin for its cost-effectiveness, high purity, and consistent performance—delivering exceptional outcomes without unnecessary additives.
Rather than focusing solely on price per unit, we prioritize safety, efficacy, and personalized results to ensure you get the most from your investment in wrinkle treatment.
Choosing Xeomin for Smoother, Natural-Looking Results at Perizia Aesthetics
At Perizia Aesthetics in Jupiter, FL, we recommend Xeomin as an effective, highly purified neuromodulator for reducing fine lines and wrinkles. While both Xeomin and Botox are FDA-approved and widely trusted, our experienced team suggests Xeomin for patients seeking a cleaner formulation without unnecessary additives.
During your personalized consultation, we’ll assess your goals, review your treatment history, and explain why Xeomin may be the ideal choice for your aesthetic needs.
To get started, call us today at 561-318-7895 or schedule your consultation online.
Conclusion
At Perizia Aesthetics, we recommend Xeomin for patients seeking a clean, effective solution to dynamic wrinkles. Its purified, protein-free formulation helps minimize the risk of antibody resistance, making it a trusted choice for long-term results. While Botox remains a reputable option with decades of clinical use, Xeomin’s additive-free design aligns with our commitment to precision, purity, and patient safety.
Both treatments can smooth frown lines, soften crow’s feet, and refresh your appearance—but we proudly provide Xeomin as our preferred neuromodulator in Jupiter, Florida. Ready to experience smoother, more confident skin?
Call 561-318-7895 or book your appointment online to get started.
